DART-01: Developmental and Reproductive Toxicity
Growth and Clinical Finding Tables (I), Pathology Tables (PA), Developmental and Reproductive Tables (R) from NTP Developmental and Reproductive Toxicity Studies
Food consumption table (I06) was updated to include statistical analysis on October 26, 2017.
Updated graphs (I03) for higher quality image. Fetal summary (R10 and R11) and gross pathology (PA46) data tables were updated to reflect new statistics (October 15, 2018)
DOI: https://doi.org/10.22427/NTP-DATA-DART-01
TCPP is produced as a mixture of four isomers. All NTP studies of TCPP have utilized a procured isomeric mixture and details are provided in the associated DART Report. The data tables herein reference TCPP with CASRN 13674-84-5, which represents the major isomer of the TCPP mixture.
Updated graphs (I03) for higher quality image. Fetal summary (R10 and R11) and gross pathology (PA46) data tables were updated to reflect new statistics (October 15, 2018)
DOI: https://doi.org/10.22427/NTP-DATA-DART-01
TCPP is produced as a mixture of four isomers. All NTP studies of TCPP have utilized a procured isomeric mixture and details are provided in the associated DART Report. The data tables herein reference TCPP with CASRN 13674-84-5, which represents the major isomer of the TCPP mixture.
DART-01: Tris(Chloropropyl)phosphate (TCPP)
Developmental and Reproductive Toxicity
Prenatal Developmental Toxicity Dose Range Finding Study - Rats
- I01 - Animal Removal Summary (37 KB)
- I03 - Growth Curve (50 KB)
- I04 - Mean Body Weights and Survival (102 KB)
- I04G - Mean Body Weight Gain (51 KB)
- I05 - Clinical Observations Summary (114 KB)
- I06 - Mean Feed Consumption (58 KB)
- PA46 - Gross Pathology Summary (94 KB)
- R09 - Uterine Content Summary (75 KB)
- R10 - Fetal Defects (36 KB)
- R11 - Fetal Defect Summary (42 KB)
- R13 - Fetal Defect Cross Reference Summary (36 KB)
Prenatal Developmental Toxicity Dose Range Finding Individual Animal Data - Rats
- Individual Animal Body Weight Data (37 KB)
- Individual Animal Clinical Observations Data (51 KB)
- Individual Animal Consumption Data (18 KB)
- Individual Animal Gross Pathology Data (11 KB)
- Individual Animal Removal Reasons (12 KB)
- Individual Animal Teratology Dam Data (11 KB)
- Individual Animal Teratology Implant Data (34 KB)
Prenatal Developmental Toxicity Study - Rats
- I01 - Animal Removal Summary (30 KB)
- I03 - Growth Curve (49 KB)
- I04 - Mean Body Weights and Survival (102 KB)
- I04G - Mean Body Weight Gain (51 KB)
- I05 - Clinical Observations Summary (91 KB)
- I06 - Mean Feed Consumption (58 KB)
- PA06 - Organ Weights Summary (40 KB)
- PA46 - Gross Pathology Summary (77 KB)
- R09 - Uterine Content Summary (75 KB)
- R10 - Fetal Defects (215 KB)
- R11 - Fetal Defect Summary (98 KB)
- R13 - Fetal Defect Cross Reference Summary (153 KB)
Prenatal Developmental Toxicity Individual Animal Data - Rats
- Individual Animal Body Weight Data (94 KB)
- Individual Animal Clinical Observations Data (127 KB)
- Individual Animal Consumption Data (32 KB)
- Individual Animal Gross Pathology Data (15 KB)
- Individual Animal Organ Weight Data (19 KB)
- Individual Animal Removal Reasons (14 KB)
- Individual Animal Teratology Dam Data (21 KB)
- Individual Animal Teratology Implant Data (413 KB)