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Study Information
Study Attribute Value
CEBS Accession Number: 002-01604-0029-0000-4
Chemical Name: Acrylamide
CASRN: 79-06-1
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 549305_CA
Study Result: Positive (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 12/05/85 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0033
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 6.50 ± 1.18 0.0000
Test Chemical Acrylamide 
40         
 7 2.86 ± 1.22 0.0304
  
80         
 7 1.14 ± 0.59 0.4247
  
160         
 8 4.25 ± 1.03 0.0020
Vehicle Control No Stressor 
 0         
 8 1.00 ± 0.53 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed