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Study Information
Study Attribute Value
CEBS Accession Number: 002-02044-0016-0000-9
Chemical Name: Diglycidyl resorcinol ether (DGRE)
CASRN: 101-90-6
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 389996_CA
Study Result: Positive

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 01/30/86 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0080
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
101         
 8 14.50 ± 1.76 0.0000
Test Chemical Diglycidyl resorcinol ether (DGRE) 
62.5       
 8 1.50 ± 0.63 0.6101
  
125         
 8 1.00 ± 0.53 0.8188
  
250         
 8 4.00 ± 1.07 0.0284
Vehicle Control No Stressor 
 0         
 8 1.75 ± 0.59 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 10/02/86 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0000
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 19.50 ± 2.82 0.0000
Test Chemical Diglycidyl resorcinol ether (DGRE) 
200         
 8 5.00 ± 1.31 0.0105
  
300         
 8 18.50 ± 2.80 0.0000
  
400         
 8 20.25 ± 5.44 0.0000
Vehicle Control No Stressor 
 0         
 8 2.00 ± 0.76 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed