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Study Information
Study Attribute Value
CEBS Accession Number: 002-02194-0017-0000-6
Chemical Name: Furfural
CASRN: 98-01-1
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 991433_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 02/19/87 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.9160
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 6.00 ± 1.60 0.0123
Test Chemical Furfural 
50         
 8 0.75 ± 0.37 0.9845
  
100         
 8 0.75 ± 0.53 0.9845
  
200         
 8 1.25 ± 0.53 0.9351
Vehicle Control No Stressor 
 0         
 8 2.75 ± 0.65 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 10/27/87 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.8293
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 10.25 ± 1.91 0.0000
Test Chemical Furfural 
50         
 8 3.00 ± 1.41 0.0763
  
100         
 8 1.00 ± 0.38 0.7378
  
200         
 8 1.25 ± 0.53 0.6193
Vehicle Control No Stressor 
 0         
 8 1.50 ± 0.50 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed