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Study Information
Study Attribute Value
CEBS Accession Number: 002-02745-0013-0000-4
Chemical Name: Propyl gallate
CASRN: 121-79-9
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 299865_CA
Study Result: Positive

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 02/01/88 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0115
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 13.00 ± 0.85 0.0000
Test Chemical Propyl gallate 
100         
 8 3.00 ± 0.85 0.9001
  
200         
 8 3.50 ± 0.91 0.8130
  
400         
 7 7.71 ± 1.11 0.0457
Vehicle Control No Stressor 
 0         
 8 4.75 ± 0.84 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 04/17/89 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0042
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 13.75 ± 1.58 0.0000
Test Chemical Propyl gallate 
100         
 8 1.50 ± 0.82 0.5922
  
200         
 8 1.75 ± 0.45 0.4851
  
400         
 8 4.25 ± 1.16 0.0222
Vehicle Control No Stressor 
 0         
 7 1.71 ± 0.68 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed