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Study Information
Study Attribute Value
CEBS Accession Number: 002-02797-0015-0000-3
Chemical Name: Selenium sulfide
CASRN: 7446-34-6
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 023793_CA
Study Result: Positive

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 03/08/89 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.0000
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
25         
 8 15.50 ± 2.38 0.0000
Test Chemical Selenium sulfide 
5         
 8 2.75 ± 0.92 0.1101
  
10         
 8 8.50 ± 1.40 0.0000
  
20         
 8 12.50 ± 2.29 0.0000
Vehicle Control No Stressor 
 0         
 8 1.50 ± 0.50 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 03/22/89 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0115
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 13.00 ± 0.85 0.0000
Test Chemical Selenium sulfide 
5         
 8 3.25 ± 1.13 0.0520
  
10         
 8 2.00 ± 0.76 0.2949
  
20         
 8 4.50 ± 0.98 0.0064
Vehicle Control No Stressor 
 0         
 8 1.50 ± 0.50 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed