
-   TREM2 mRNA levels were increased in COPD lung tissues compared with non-COPD lung tissues. The ratio of TREM2/TREM1 mRNA levels correlates with decreased lung function as measured by FEV1 and FEV1/FVC [PMID: 29017955].
-   TREM2 mRNA level was elevated in bronchoalveolar lavage (BAL) cells from Idiopathic Pulmonary Fibrosis (IPF) patients and the TREM2 level in BAL cells was strongly negatively correlated with the survival time of IPF patients [PMID: 37003186].
-   Gene expression of Trem2 was significantly increased in the rat lung after bleomycin treatment [PMID: 24278517].
-   TREM2 mRNA and protein expression in the whole lung was significantly higher in the ovalbumin-sensitized and -challenged mice [PMID: 28928485].
