
-   Transcriptional profiling identified PLA2G2A as a potential biomarker for Phospholipidosis (PLD) detection in rat heart and blood tissues. The expression of PLA2G2A was found to be altered under toxic conditions induced by amiodarone treatment [PMID: 25580480].
-   Increased gene expression of PLA2IIA was detected in epicardial adipose tissue (EAT) from coronary artery disease (CAD) as compared with non-CAD (NCAD). Secretory type II phospholipase A2 (sPLA2-IIA) was ranked as the highest gene coding for potentially secreted proteins with the highest overexpression in epicardial adipose tissue (EAT) in both coronary artery disease (CAD) and non-CAD (NCAD). Secretory type II phospholipase A2 was overexpressed in patients with coronary artery disease [PMID: 20008021].
