
-   In rat model of hepatocellular carcinoma, administration of curcumin induced GPx2 mRNA expression [PMID: 25640336].
-   Expression of GPx2 was elevated in rat liver in the model of hepatic injury caused by the following compounds: bromobenzene [PMID: 17538237], beta-naphthoflavone [PMID: 18164116], indole-3-carbinol and flutamide [PMID: 21203749], piperonyl butoxide [PMID: 17498859], MeIQx [PMID: 17342310].
-   Catalase and glutathione peroxidase mRNA levels, which include Gpx2, correlated significantly with liver cell polyploidy. The correlation between glutathione peroxidase mRNA levels and the number of cells in the greater than G2 and M phase of the cell cycle was observed [PMID: 8560485].
