
-   ZDHHC2 gene expression was upregulated and linked to changes in liver swelling, or hepatomegaly in rats exposed to carcinogens [PMID: 25058030].
-   ZDHHC2 gene expression was frequently decreased in in human hepatocellular carcinoma. Loss of heterozygosity (LOH) on ZDHHC2 was associated with early metastatic recurrence of HCC following liver transplantation and was correlated with tumor size and portal vein tumor thrombi [PMID: 24995331].
-   Zdhhc2 gene expression was identified as carcinogenic liver hypertrophy related using toxicogenomic data from TG-GATEs [PMID: 28108177].
