
-   Size: 195 amino acids
-   Molecular mass: 21841 Da
-   Protein Accession: P05019
-   Family: Belongs to the insulin family.
-   Domains: IGF-I, Insulin-like, Insulin-like_growth_factor, Insulin-like_sf, Insulin_CS, Insulin_family
-   The 3D structure of tyrosine kinase receptors, including IGF-1, and their hormone-bound complexes, has been studied using mutagenesis and kinetic studies, revealing two binding sites on the hormone surface, with emphasis on modifications of the hypothetical binding site 2, and these findings are discussed in light of recent cryoEM structures of hormone complexes with IR and IGF-1R [[PMID: 37717985]](https://www.ncbi.nlm.nih.gov/pubmed/37717985).
