
-   Ficolin B is expressed within mouse peritoneal exudate macrophages and its expression is up-regulated upon macrophage activation [PMID: 16690015].
-   The level of ficolin B expression in murine bone marrow was increased after stimulation with LPS (1 and 6 hrs post stimulation). This was followed by a downregulation of expression, causing mRNA levels to return to baseline 24 h post LPS challenge. LPS-induced inflammation can induce a significant ficolin response, suggesting that the murine ficolins are acute phase reactants with increase in both mRNA expression and protein levels during systemic inflammation [PMID: 30818229].
-   C-reactive protein (CRP) collaborates with plasma lectins to boost immune response against bacteria. hCRP interacts with ficolin, which stabilizes CRP binding to bacteria and activates the lectin-mediated complement pathway [PMID: 17581635].
-   LncRNA AK036396 inhibits maturation and accelerates immunosuppression of polymorphonuclear myeloid-derived suppressor cells by enhancing the stability of ficolin b [PMID: 32102837].
