
-   Protein Accession: O95154
-   Size: 331 amino acids
-   Molecular mass: 37206 Da
-   Domains: NADP_OxRdtase_dom, NADP_OxRdtase_dom_sf
-   Blocks: Aldo/keto reductase
-   Family: Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily. [PMID: 10383892].
-   AKR7A3 is soluble NAD(P)(H) oxidoreductases that primarily reduce aldehydes to primary and secondary alcohols [PMID: 16970545]. This enzyme is likely protect against aflatoxin mediated hepatotoxicity [PMID: 10383892].
-   Similar to AKR1B1, AKR7A3 also has an ORE (5'-TGGAAAATCA-CCGC-3') or tonicity response element (TonE) in its promoter. This element might be responsible for the response to osmotic stress through the NFkappaB signal transduction pathways [PMID: 17537398].
