
-   Osteosarcoma patients with lower mRNA levels of cyclin-dependent kinase 1 (CDK1) and topoisomerase II alpha had better prognoses [PMID: 34156352].
-   The expression of Cdk1 decreases when the expression of Gdf15 in cardiac fibroblasts is suppressed. GDF15 promotes cardiac fibrosis and proliferation of cardiac fibroblasts via the MAPK/ERK1/2 pathway after irradiation in rats [PMID: 34019665].
-   Oral administration of EHP-101 prevents and inhibits cardiac inflammation and fibrosis. EHP-101 inhibited the gene expression of CDK1 in myocardial tissue [PMID: 34385107].
-   The cell cycle-related gene cdk1 showed strong differential expression between fetal and adult hearts, thus being potent candidates to be targeted in human cardiac regeneration strategies [PMID: 32167779].
-   CDK1/FBXW7 facilitates degradation and ubiquitination of MLST8 to inhibit progression of renal cell carcinoma [PMID: 34741373].
-   The specific activity of CDK1 and CDK2 is a novel prognostic indicator for early breast cancer. Tumors with high CDK1SA and high CDK2SA showed significantly poorer 5-year relapse-free survival than those with low CDK1SA and low CDK2SA [PMID: 17956886].
-   The combination of CDC2 and HOXA13 distinguished between grade 1 to 2 transitional cell carcinoma (TCC) of the bladder and grade 3 or stage > or =T1 TCCs with approximately 80% specificity and sensitivity [PMID: 18245534].
-   CDK1 was markedly upregulated at both the mRNA and protein level in lung adenocarcinoma (LUAD). Overexpression of CDK1 was related to poor clinical outcomes [PMID: 36950551]. High gene expression levels of CDK1 and CDC20 in patients with lung squamous cell carcinoma are associated with worse prognosis [PMID: 34307447].
-   CDK1 was one of the hub genes that are differentially expressed between melanoma metastases and primary melanoma tissues [PMID: 35054979].
-   CDK1 was defined as one of the ten hub genes that are common differentially expressed genes (DEGs) between inflammatory bowel disease (IBD) and cervical cancer (CC) [PMID: 36049413].
-   Circ-NOLC1 promotes epithelial ovarian cancer tumorigenesis and progression by binding ESRP1 and modulating CDK1 and RhoA expression. The overexpression of circ-NOLC1 significantly increased CDK1 protein and mRNA expression levels [PMID: 33483472].
-   A total of 10 key genes were identified and found significantly associated with poor survival outcome for patients with retinoblastoma based on survival analyses, including CDK1 [PMID: 33217867].
-   Overexpression of CDK1 was identified as one of the differentially expressed genes in oral squamous cell carcinoma (OSCC). And levels of CDK1 and NDRG1 were associated with poorly differentiated tumors [PMID: 15645429].
