
-   Microarray data analysis of datasets involving Inflammatory bowel disease (IBD) affected and ankylosing spondylitis (AS) affected vs controls were done to explore the differentially expressed genes (DEGs). The INHBA gene was found to be differentially expressed in datasets involving IBD affected and AS affected vs controls. This study also suggests that TMTC1, INBHA, TMEM45A and SAMD9L DEGs and their pathways might have the potential to be exploited as drug targets and biomarkers in the diagnosis and/or treatment of IBD linked arthritis [PMID: 29147967].
-   INHBA is part of a 40-gene signature identified by differential gene expression analysis in the following three comparisons: colorectal adenoma (CRA) vs. normal colorectal mucosa (NOR), colorectal carcinomas (CRCs) vs. CRA and CRC vs. NOR. Changes in the expression of INHBA were observed from the CRA stage and maintained in colorectal cancer (CRC). The study associates INHBA with the progression from colorectal adenoma to colorectal cancer [PMID: 20878084, PMID: 24516561].
