
**NCBI Gene Summary**: Predicted to enable ubiquitin protein ligase activity. Predicted to act upstream of or within protein ubiquitination. [provided by Alliance of Genome Resources, Apr 2022]

**GeneCards Summary**: NEURL3 (Neuralized E3 Ubiquitin Protein Ligase 3) is a Protein Coding gene. Diseases associated with NEURL3 include Hepatitis C Virus. Among its related pathways are 2q11.2 copy number variation syndrome. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin-protein transferase activity. An important paralog of this gene is NEURL1B.

**UniProtKB/Swiss-Prot Summary**: E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands.
