
-   Size: 99 amino acids
-   Molecular mass: 11025 Da
-   Protein Accession: P13500
-   Family: Belongs to the intercrine beta (chemokine CC) family
-   Domains: Chemokine_b/g/d, Chemokine_CC_CS, Chemokine_IL8-like_dom, Interleukin_8-like_sf
-   Acts as a ligand for C-C chemokine receptor CCR2 [PMID: 9837883, PMID: 10587439, PMID: 10529171]. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions [PMID: 9837883, PMID: 10587439]. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils [PMID: 8627182, PMID: 9792674, PMID: 8195247]. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis [PMID: 8107690].
