
## **Compounds that increase expression of the gene:**

-   (25R)-cholest-5-ene-3beta,26-diol [PMID: 33880675]
-   1,2-dichlorobenzene [PMID: 10614693]
-   1,2-dichloroethane [PMID: 28960355]
-   1,4-dichlorobenzene [PMID: 9398495]
-   1-naphthyl isothiocyanate [PMID: 17522070, PMID: 25380136, PMID: 30723492, PMID: 12883083]
-   17alpha-ethynylestradiol [PMID: 14976129]
-   2,2',4,4',5,5'-hexachlorobiphenyl [PMID: 20005886, PMID: 21851831]
-   2,3,7,8-tetrachlorodibenzodioxine [PMID: 15800033, PMID: 16891777, PMID: 20005886, PMID: 21846477, PMID: 21851831, PMID: 31536130]
-   2-acetamidofluorene [PMID: 11350689, PMID: 19167416]
-   4,4'-diaminodiphenylmethane [PMID: 18648102]
-   DDT [PMID: 23684557]
-   Dibromoacetonitrile [PMID: 21986297]
-   GW 4064 [PMID: 31437187]
-   GW 7647 [PMID: 34081128]
-   N-ethyl-N-nitrosourea [PMID: 19100860]
-   N-nitrosodiethylamine [PMID: 10425313, PMID: 19100860, PMID: 20583210, PMID: 27058323, PMID: 33290806, PMID: 17106253, PMID: 19418558, PMID: 19638242, PMID: 19642983, PMID: 29698782, PMID: 7576107, PMID: 7910516]
-   N-nitrosodimethylamine [PMID: 25380136]
-   Nodularin [PMID: 27061667]
-   aflatoxin B1 [PMID: 25378103]
-   arsenous acid [PMID: 26046465]
-   benzo[a]pyrene [PMID: 19408242]
-   bis(2-ethylhexyl) phthalate [PMID: 9398495]
-   bromobenzene [PMID: 32479839]
-   cadmium dichloride [PMID: 15551354, PMID: 16600092, PMID: 21181359]
-   chloroform [PMID: 11532874]
-   chlorohydrocarbon [PMID: 24355586]
-   cyclosporin A [PMID: 27989131]
-   diarsenic trioxide [PMID: 26046465]
-   dichloroacetic acid [PMID: 10774822, PMID: 11532874, PMID: 28962523]
-   disodium selenite [PMID: 16944776]
-   ethanol [PMID: 35149083, PMID: 35608386]
-   flutamide [PMID: 24136188]
-   furan [PMID: 24183702, PMID: 37517673]
-   leflunomide [PMID: 28988120]
-   lipopolysaccharide [PMID: 16415329]
-   microcystin-LR [PMID: 28062358, PMID: 17654400]
-   naloxone [PMID: 17522070]
-   nitrofurazone [PMID: 15945272]
-   okadaic acid [PMID: 31115591]
-   oleanolic acid [PMID: 18706400, PMID: 18706400]
-   ortho-Aminoazotoluene [PMID: 21672546]
-   perfluorooctane-1-sulfonic acid [PMID: 24301089]
-   perfluorooctanoic acid [PMID: 19162173, PMID: 36849026, PMID: 18281256]
-   phenobarbital [PMID: 19084549, PMID: 19162173, PMID: 19482888]
-   phorbol 13-acetate 12-myristate [PMID: 17106253]
-   pirinixic acid [PMID: 11857776, PMID: 16377806]
-   pregnenolone 16alpha-carbonitrile [PMID: 28903501]
-   propiconazole [PMID: 21278054]
-   rotenone [PMID: 10630619]
-   sertraline [PMID: 24865413]
-   sulfur dioxide [PMID: 19408242]
-   tamoxifen [PMID: 12841865, PMID: 17219426]
-   taurocholic acid [PMID: 27151938]
-   thioacetamide [PMID: 22659510, PMID: 23411599, PMID: 28903497, PMID: 34492290]
-   trichloroacetic acid [PMID: 10774822, PMID: 11532874]
-   trichloroethene [PMID: 10774822, PMID: 21135412]
-   triclosan [PMID: 30238133]
-   triphenyl phosphate [PMID: 35776891]
-   troglitazone [PMID: 19631733]
-   trovafloxacin [PMID: 35537566]

## **Compounds that decrease expression of the gene:**

-   Antrocin [PMID: 36565974]
-   Cinobufagin [PMID: 21215801]
-   Destruxin B [PMID: 24434019]
-   acetohydrazide [PMID: 15282401]
-   all-trans-retinoic acid [PMID: 1917145]
-   amiodarone [PMID: 17202758]
-   atorvastatin calcium [PMID: 29630879]
-   bisphenol A [PMID: 32145629]
-   clofibrate [PMID: 12604186]
-   curcumin [PMID: 15911101]
-   dexamethasone [PMID: 17522070]
-   gamma-hexachlorocyclohexane [PMID: 17785943]
-   genistein [PMID: 21078540, PMID: 21078540]
-   mancozeb [PMID: 36007320]
-   methotrexate [PMID: 17400583]
-   mifepristone [PMID: 12605714]
-   obeticholic acid [PMID: 27939613]
-   ouabain [PMID: 21215801]
-   paclitaxel [PMID: 27496854]
-   promethazine [PMID: 28903497]
-   quinidine [PMID: 17522070]
-   resveratrol [PMID: 25905778]
-   royal jelly [PMID: 27496854]
-   selumetinib [PMID: 17876044]
-   silibinin [PMID: 27746612]
-   theophylline [PMID: 17522070]
