
## **Compounds that increase expression of the gene:**

-   1-naphthyl isothiocyanate [PMID: 30723492]
-   2-acetamidofluorene [PMID: 19167416, PMID: 22584684]
-   3,3',4,4',5-pentachlorobiphenyl [PMID: 23196670]
-   4,4'-diaminodiphenylmethane [PMID: 25380136]
-   GW 4064 [PMID: 31437187]
-   N-nitrosodiethylamine [PMID: 19887370, PMID: 19638242, PMID: 17854601]
-   N-nitrosodimethylamine [PMID: 25380136]
-   O-methyleugenol [PMID: 23411599]
-   Triptolide [PMID: 23639586]
-   acetamide [PMID: 31881176]
-   benzophenone [PMID: 22584684]
-   chlorendic acid [PMID: 22584684]
-   fenbendazole [PMID: 23411599]
-   fipronil [PMID: 23962444]
-   methapyrilene [PMID: 22584684]
-   phenobarbital [PMID: 19482888, PMID: 23091169, PMID: 24690595, PMID: 33549593, PMID: 19162173]
-   piperonyl butoxide [PMID: 23411599]
-   pirinixic acid [PMID: 16377806, PMID: 17483499]
-   pregnenolone 16alpha-carbonitrile [PMID: 22698814]
-   propiconazole [PMID: 21278054]
-   tamoxifen [PMID: 12841865]
-   thioacetamide [PMID: 23411599, PMID: 34492290]
-   trabectedin [PMID: 12154027]
-   trichloroethene [PMID: 25549359]

## **Compounds that decrease expression of the gene:**

-   Diosbulbin B [PMID: 30145177, PMID: 30145177]
-   Licochalcone A [PMID: 30055311]
-   azathioprine [PMID: 22623647]
-   benzo[a]pyrene [PMID: 31555880]
-   buspirone [PMID: 24136188]
-   butane-2,3-dione [PMID: 37399938]
-   dioscin [PMID: 29990575]
-   leflunomide [PMID: 28988120, PMID: 24136188]
-   levofloxacin [PMID: 24136188]
-   methamphetamine [PMID: 28341135]
-   nimesulide [PMID: 24136188]
-   orlistat [PMID: 30667213]
-   paclitaxel [PMID: 18058816]
-   paracetamol [PMID: 29067470]
-   simvastatin [PMID: 20878096]
-   sodium arsenite [PMID: 32844245]
-   trovafloxacin [PMID: 24136188, PMID: 35537566]
