
-   p85: The antiinflammatory effect of KIM-1 expression was due to the interaction of KIM-1 with p85 and subsequent PI3K-dependent downmodulation of NF-kappaB [PMID: 25751064].
-   LMIR5: TIM1 interacted only with LMIR5 among the LMIR family, whereas LMIR5 interacted with TIM4 as well as TIM1 [PMID: 20566714].
-   IgA: Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions [PMID: 17229699].
-   DYNLT1: Dynein light chain Tctex-type 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. May also be a accessory component of axonemal dynein [PMID: 29693725]
-   TIMD4: T-cell immunoglobulin and mucin domain-containing protein 4; Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1 (By similarity). Belongs to the immunoglobulin superfamily - TIM family. [[https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000274532 9606.ENSP00000487363](https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000274532%0D9606.ENSP00000487363)].
-   CST3: Cystatin-C; As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity; Belongs to the cystatin family. [[https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363 9606.ENSP00000381448](https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363%0D9606.ENSP00000381448)].
-   LCN2: Neutrophil gelatinase-associated lipocalin; Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. [[https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363 9606.ENSP00000362108](https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363%0D9606.ENSP00000362108)].
-   ALB: Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. [[https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363 9606.ENSP00000295897](https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363%0D9606.ENSP00000295897)].
-   FABP1: Fatty acid-binding protein, liver; Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity). Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.[[https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363 9606.ENSP00000295834](https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363%0D9606.ENSP00000295834)].
-   IGFBP7: Insulin-like growth factor-binding protein 7; Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.[[https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363 9606.ENSP00000295666](https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363%0D9606.ENSP00000295666)].
-   IL18: Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable). Belongs to the IL-1 family.[[https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363 9606.ENSP00000280357](https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363%0D9606.ENSP00000280357)].
-   OGA: Protein O-GlcNAcase; [Isoform 1]: Cleaves GlcNAc but not GalNAc from O- glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta- GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro). Does not bind acetyl-CoA and does not have histone acetyltransferase activity.[[https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363 9606.ENSP00000354850](https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363%0D9606.ENSP00000354850)].
-   SPP1: Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.
-   TFF3: Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).[[https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363 9606.ENSP00000378517](https://string-db.org/newstring_cgi/show_edge_details.pl?identifiers=9606.ENSP00000487363%0D9606.ENSP00000378517)].
