
-   In murine primary corneal epithelial cells (mPCECs) derived from IPS-1 knockout mice stimulated with polyI:C, Neurl3 mRNA expression was dominantly upregulated. TLR3 knockout specifically downregulated Neurl3 gene expression. This suggests that Neurl3 production may be regulated by the TLR3 signaling pathway [PMID: 37193897].
-   LINCR expression was shown to be induced by LPS and inflammatory cytokines in alveolar type II cells. The highest levels of LINCR gene expression were produced by the combination of TNF-alpha and IFN-gamma together with LPS or IL-1 beta [PMID: 15936721].
-   LINCR was identified as a glucocorticoid-attenuated response gene induced in the lung during endotoxemia [PMID: 15936721, PMID: 16113446].
