
-   The DNA methylation of GSTM1 was significantly increased in ovarian cancer (OC) compared to normal samples leading to decreased mRNA expression of GSTM1 in OC [PMID: 35965498].
-   The mood stabilizers like lithium or valproate can induce the expression of both GSTM1 and GSTA4, and they inhibit oxidative damage to lipids as well as proteins, therefore they protect the brain from exotoxicity [PMID: 16005436].
-   Low expression of GSTM1 and GSTM2 were significantly associated with favorable prognosis in COAD. These two genes may serve as potential biomarkers of COAD prognosis [PMID: 32539715]. Also, GSTM1 expression levels in COAD positively correlated with dendritic cell, B cell, neutrophil, and macrophage infiltration [PMID: 36636093].
-   GSTM1 gene expression was down-regulated in mice bladder carcinogenesis and is usually deleted in human urothelial carcinoma [PMID: 27404495].
-   Subjects carrying GSTM1-null genotype seemed to have a higher susceptibility to DNA damage induced by tobacco smoke than GSTM1-positive ones [PMID: 17644396].
-   Reduction of Gstm1 gene expression in the stroke-prone spontaneously hypertension rat contributes to increased oxidative stress [PMID: 15699453].
