
-   FKBP5 gene expression is induced by hypergravity through the vestibular system in anti-gravity muscle of mice [PMID: 27680313].
-   The transcript levels of Fkbp5 was downregulated under the treatment of CTRND05, a monoclonal antibody targeting corticotropin-releasing factor (CRF) and suppressing the hypothalamic-pituitary-adrenal (HPA) axis. In mice, CTRND05 blocks stress-induced corticosterone increases, counteracts effects of chronic variable stress. CTRND05 treatment also induces lean mass gain and skeletal muscle hypertrophy [PMID: 31467037].
-   FKBP5 gene expression decreased in muscles of calves administered with dexamethasone and estradiol, whereas increased in the longissimus lumborum and vastus lateralis muscle of prednisolone-treated group. FKBP5 gene expression in skeletal muscle as a potential biomarker for illegal glucocorticoid treatment in veal calves [PMID: 32992127].
-   FKBP5 expression decreased in adipose tissue (AT) of overweight/obese subjects and increased in muscle after insulin infusion [PMID: 35212883].
