
-   LILRB4 is induced in monocytes by type I IFNs, which are upregulated early in the infectious process and critical to contain the viral expansion [PMID: 25551576].
-   Porphyromonas gingivalis (Pg) lipopolysaccharide (LPS) enhanced the tolerogenic properties of antigen-presenting cells (APCs) and up-regulated ILT-3 and B7-H1 expression [PMID: 15111638].
-   Vitamin D3 and its nuclear receptor bind to the promoter region of LILRB4 and drive LILRB4 expression [PMID: 32325790].
-   IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells [PMID: 17163451].
-   ILT3, an inhibitor of T cell activation, is reduced on blood monocytes during multiple sclerosis relapses and is induced by interferon beta-1b [PMID: 20007427].
-   Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1,25-dihydroxyvitamin D3 [PMID: 16030186].
-   Tryptophan deprivation induces inhibitory receptors ILT3 and ILT4 on dendritic cells favoring the induction of human CD4+CD25+ Foxp3+ T regulatory cells [PMID: 19535644].
-   Aspirin-treated human DCs up-regulate ILT-3 and induce hyporesponsiveness and regulatory activity in responder T cells [PMID: 16869801, PMID: 17219690].
-   Fat mass and obesity-related protein (FTO), an RNA N6-methyladenosine (m6A) demethylase, positively regulates the expression of LILRB4 in monocytic AML cells by inhibiting YTH N6-methyladenosine RNA binding protein 2 (YTHDF2)-mediated decay of LILRB4 mRNA m6A modification [PMID: 32531268].
