
-   **NCBI Gene Summary**: The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
    
-   **GeneCards Summary**: MLC1 (Modulator Of VRAC Current 1) is a Protein Coding gene. Diseases associated with MLC1 include Megalencephalic Leukoencephalopathy With Subcortical Cysts 1 and Megalencephalic Leukoencephalopathy With Subcortical Cysts. Among its related pathways are MAPK-Erk Pathway and Colorectal Cancer Metastasis. Gene Ontology (GO) annotations related to this gene include transporter activity and obsolete protein transporter activity.
    
-   **UniProtKB/Swiss-Prot Summary**: Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.
    
