
-   TLR1 was identified as one of IFN regulated genes (IRGs) based on expression analysis of over 40 IFN-regulated datasets collected in the Interferome database [PMID: 18996892].
-   TLR1 is down regulated in peripheral blood mononuclear cells (PBMC) of Multiple Sclerosis (MS) patients and up regulated in patients treated with interferon-beta [PMID: 17467740, PMID: 17404290].
