
-   The rTcpA protein of V. cholerae moderately stimulated the expression of tlr4 and overexpressed tlr1 in the human gut epithelium, both of which are supposed to induce a mucosal protective response against bacterial infection [PMID: 33059058].
-   Induction of TLR1 mRNA expression was observed in neonatal necrotizing enterocolitis (NEC) compared with dam-fed controls in rat [PMID: 19608731].
-   TLR1 expression was lower in inflamed colonic epithelial cells and lamina propria cells compared with normal colonic tissue [PMID: 12538701].
-   Toll-like receptor-1 polymorphisms influences disease extension in inflammatory bowel diseases. A positive association between TLR1 R80T and pancolitis in ulcerative colitis (UC) was found. In Crohn's disease (CD), a negative association between ileal disease involvement and TLR1 S602I was found [PMID: 16374251].
