
-   The TNF ligand TWEAK binds to Tnfrsf12a, leading to its activation and the expression of pro-survival, pro-proliferative and homing receptor genes in the mesenchymal stem cells [PMID: 17124496].
-   TweakR mRNA levels were significantly elevated above unstimulated levels following PMA, FBS, PDGF-BB, EGF, FGF-2, or Ang II treatment of rat aortic smooth muscle cells (SMC) indicating that TweakR is a growth factor-regulated gene in vascular SMC [PMID: 11728344].
-   MicroRNA-19a targets Fn14 and prevents tubular damage in septic acute kidney injury (AKI) [PMID: 32670778].
-   Tcfrsf12a gene expression in the kidney tissue was significantly up-regulated following oral doses of melamine in rats [PMID: 23052191].
