
-   Reg3beta is associated with cardiac inflammation and provides prognostic information in patients with acute coronary syndrome. Elevated Reg3-beta levels on admission were associated with an increased risk of death independent of cardiovascular risk factors and hs-CRP [PMID: 29544958].
-   The gene expression of Reg3-beta, Reg3-gamma, and Reg4 is strongly increased in myocardial tissue after myocardial infarction (MI) in mouse and human hearts. Regenerating islet-derived protein 3 beta (Reg3-beta) is a factor directing macrophages to sites of myocardial injury [PMID: 29850784].
-   The regenerated gene (Reg)2/pancreatitis-associated protein (PAP)1 messenger RNA (mRNA) levels were significantly increased in in cardiomyocytes under active myocarditis than normal [PMID: 18774541].
