
-   Protein Accession: Q13753
-   Size: 1193 amino acids
-   Molecular mass: 130976 Da
-   Domains: EGF-like_dom, Laminin_IV, LE_dom
-   Blocks: Laminin B
-   Family: None
-   The exon-intron structure of the human laminin B2 chain gene was elucidated spanning 2 kilobase pairs (kb) of the 5'-flanking region, 58 kb of the structural gene and 10 kb of the 3'-flanking region. The entire gene was shown tocontain 28 exons. The promoter region has no TATA or CAAT boxes whereas it contains five GC boxes and three AP2-like binding sites [PMID: 1985895]. The gene analysis demonstrated that two different size gamma 2 chain cDNAs [PMID: 8786121, PMID: 1383240] are the result of alternative splicing. The longer gamma 2 chain is formed by using the coding sequence of the last exon 23, while the shorter gamma 2\* chain is formed by using only 22 exons, together with part of the 5' end of intron 22 [PMID: 8786121].
