
**NCBI Gene Summary**: Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004]

**GeneCards Summary**: AKR7A3 (Aldo-Keto Reductase Family 7 Member A3) is a Protein Coding gene. Diseases associated with AKR7A3 include Cytochrome P450 Oxidoreductase Deficiency. Among its related pathways are Metapathway biotransformation Phase I and II and Metabolism. Gene Ontology (GO) annotations related to this gene include electron transfer activity and aldo-keto reductase (NADP) activity. An important paralog of this gene is AKR7L.

**UniProtKB/Swiss-Prot Summary**: Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
