
-   In cecal ligation and puncture-induced sepsis-associated acute kidney injury (SA-AKI) mouse models, CXCL1 was identified as one of the seven hub genes. Differential expression of CXCL1 among 4,754 genes emerged from the transcriptomic profiling, suggesting its potential role in the pathological processes related to kidney damage in sepsis [PMID: 35957725].
-   Reduced expression of miR-206 in cases of progressive chronic kidney disease correlates with upregulation of CXCL1 mRNA, indicating its involvement in inflammatory pathways [PMID: 26707063].
-   The gene expression of CXCL 1, 5, and 13 significantly impacted progression-free survival outcomes in clear cell renal cell carcinoma (ccRcc) patients [PMID: 37540227].
