
-   Glomerular deposition of MBL and L-ficolin was associated with activation of the lectin pathway of complement and more pronounced histologic renal damage, as evidenced by increased mesangial proliferation, extracapillary proliferation, glomerular sclerosis, and interstitial infiltration, as well as with significantly more proteinuria. Together, these findings suggest a contribution for MBL and L-ficolin in the progression of IgA nephropathy [PMID: 16687629].
