
-   EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence [[PMID: 34342583](https://www.ncbi.nlm.nih.gov/pubmed/34342583)].
-   EPHX1 is identified as a potential modifier in pancreas and liver outcomes in Cystic Fibrosis [[PMID: 28339466](https://www.ncbi.nlm.nih.gov/pubmed/28339466)].
