
## **Compounds that increase expression of the gene:**

-   1-naphthyl isothiocyanate [PMID: 25380136, PMID: 30723492]
-   2,3,7,8-tetrachlorodibenzodioxine [PMID: 20959002]
-   2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one [PMID: 21813463]
-   2-nitrofluorene [PMID: 14600272]
-   3,3',4,4',5-pentachlorobiphenyl [PMID: 20959002]
-   4,4'-diaminodiphenylmethane [PMID: 25380136, PMID: 18648102]
-   N-nitrosodiethylamine [PMID: 19638242, PMID: 12771043, PMID: 24535843]
-   N-nitrosodimethylamine [PMID: 25380136]
-   aflatoxin B1 [PMID: 25378103]
-   ciprofibrate [PMID: 12771043]
-   clofibrate [PMID: 17585979]
-   furan [PMID: 15120968, PMID: 27387713]
-   griseofulvin [PMID: 12735108]
-   lipopolysaccharide [PMID: 27339419]
-   lithocholic acid [PMID: 20359477]
-   methapyrilene [PMID: 15120968]
-   microcystin-LR [PMID: 17654400]
-   p-toluidine [PMID: 27638505]
-   paracetamol [PMID: 24126418, PMID: 29246445]
-   phenobarbital [PMID: 19482888]
-   tetrachloromethane [PMID: 27339419, PMID: 29987408, PMID: 31919559, PMID: 31150632]
-   thioacetamide [PMID: 23411599, PMID: 34492290]

## **Compounds that decrease expression of the gene:**

-   17beta-estradiol [PMID: 32145629]
-   2-amino-14,16-dimethyloctadecan-3-ol [PMID: 32044396]
-   leflunomide [PMID: 24136188]
-   levofloxacin [PMID: 24136188]
-   sodium arsenite [PMID: 29459688]
