
-   Glucocorticoid receptor (GR) activation in multiple tissues results in rapid induction of FKBP5 transcription and translation [PMID: 21531172]. GR-induced transcription is mediated by binding of the GR to GREs, which are located in a region spanning over 100 kb and range from upstream of *FKBP5* promoter to introns 2, 5, and 7 of the gene [PMID: 20093418].
-   FKBP5 transcription is induced by androgen receptor (AR) and progestin receptor (PR) activation [PMID: 16210365, PMID: 15821585, PMID: 12746298].
-   KLF15 binds directly to the promoter region of FKBP5 and activates FKBP5 expression. This study revealed a positive regulatory role of KLF15 in myoblast differentiation and muscle regeneration by activating FKBP5 expression. [PMID: 37673339].
