CLARITY-BPA: Behavior/Brain (Patisaul)
CLARITY-BPA Program
CLARITY-BPA Data
PI: Heather Patisaul, North Carolina State University
Project Number: 5U01ES020929
DOI:
https://doi.org/10.22427/NTP-DATA-018-00012-0001-000-3
Publications
Impact of Low-Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study. Rebuli ME, Camacho L, Adonay ME, Reif DM, Aylor DL, Patisaul HB. Toxicol Sci. 2015 Dec;148(2):341-54. doi: 10.1093/toxsci/kfv163. PMID: 26209558
Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on the Neonatal Rat Hypothalamic and Hippocampal Transcriptome: A CLARITY-BPA Consortium Study.
Arambula SE, Belcher SM, Planchart A, Turner SD, Patisaul HB. Endocrinology. 2016 Oct;157(10):3856-3872. doi: 10.1210/en.2016-1339. PMID: 27571134
Effects of perinatal bisphenol A exposure on the volume of sexually-dimorphic nuclei of juvenile rats: A CLARITY-BPA consortium study. Arambula SE, Fuchs J, Cao J, Patisaul HB. Neurotoxicology. 2017 Sep 7;63:33-42. doi: 10.1016/j.neuro.2017.09.002. PMID: 28890130
Prenatal bisphenol A (BPA) exposure alters the transcriptome of the neonate rat amygdala in a sex-specific manner: a CLARITY-BPA consortium study. Sheryl E. Arambula, Dereje Jima, Heather B. Patisaul. Neurotoxicology. 2018 Mar;65:207-220. doi: 10.1016/j.neuro.2017.10.005. PMID: 29097150
Perinatal bisphenol A (BPA) exposure alters brain oxytocin receptor (OTR) expression in a sex- and region- specific manner: A CLARITY-BPA consortium follow-up study. Shannah K. Witchey, Joelle Fuchs, Heather B. Patisaul. Neurotoxicology. 2019 Jun 25;74:139-148. doi: 10.1016/j.neuro.2019.06.007. PMID: 31251963
Methods
Postnatal Day 1, Set #2
Amygdala Transcriptome Data: The data reported in Arambula et al. (2018) are not available via CEBS, since they were not part of the original work plan. Treatment group was not blinded during collection of these data. Requests for data should be addressed to the corresponding author.
Additional transcriptome-related files can be downloaded HERE
(5.5 MB)
- Brain Transcriptome Metadata (RNAseq) (21 KB)
- Hippocampal Gene Expression Data (rt-qPCR) (382 KB)
- Hypothalamic Gene Expression Data (rt-qPCR) (389 KB)
Juvenile Animals
Juvenile Brain Gene Expression Data: The data reported in Witchey et al. (2019) are not available via CEBS, since they were not part of the original work plan. Treatment group was not blinded during collection of these data. Requests for data should be addressed to the corresponding author.
Additional transcriptome-related files can be downloaded
HERE
(9.9 GB)
- Elevated Plus Maze Behavior Data (55 KB)
- Morphometric Data (104 KB)
- Open Field Behavior Data (281 KB)
Adult Animals
Additional behavior-related files can be downloaded
HERE
(24 GB)
- Elevated Plus Maze Behavior Data (50 KB)
- Open Field Behavior Data (291 KB)
- Zero Maze Behavior Data (46 KB)