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NIEHS Report 12: NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of 1,2-Dichlorobenzene (CASRN 95-50-1) in Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice via Whole Body Respiratory Exposure

One redundant endpoint in the BMD, NOEL, and LOEL Summary for Apical Endpoints table of the rat study was removed on 03 March, 2026.

DOI: https://doi.org/10.22427/NIEHS-DATA-NIEHS-12

Short-Term

Material and Methods

Theoretical Inhaled Dose

Apical Benchmark Dose Analysis - Rats

Genomic Benchmark Dose Analysis - Rats

GEO/SRA: https://www.ncbi.nlm.nih.gov/bioproject/1304578

Study Tables - Rats

Individual Animal Data - Rats

Apical Benchmark Dose Analysis - Mice

Genomic Benchmark Dose Analysis - Mice

GEO/SRA: https://www.ncbi.nlm.nih.gov/bioproject/1304935

Study Tables - Mice

Individual Animal Data - Mice

Analysis Pipeline Evaluation

BMDExpress Preview Software

BMDExpress Software: https://cebs-ext.niehs.nih.gov/cahs/file/download/2025_5Day_BMD_TM/BMDExpress_PreviewSoftware_08152025.exe